A diamond center, a magnet for fashionistas, a European cultural hub and mecca for brewmeisters – Antwerp is a multifaceted jewel. Meet the Rubens, van Dycks and van Eycks that fill its world-class museums. Admire the two oldest printing presses in the world at the sublime Museum Plantin-Moretus, a UNESCO World Heritage site. Wander through one of the world’s most beautiful train stations and down the nave of the Antwerp Cathedral, where religious paintings by Rubens and other Flemish masters are on display.

Perhaps no single edifice has had more impact on a city than the Guggenheim Museum of Bilbao. Designed by renowned architect Franck Gehry and opened in 1997, the massive, billowing, titanium-clad structure reflects the city’s revitalized relationship with the river that runs through it, and the modern collection within the museum is as impressive as the exterior. Other worthwhile museums include the Museo de Bellas Artes and the Euskal Museoa, devoted to Basque culture.

Located in southwestern France, Bordeaux is a handsome 18th-century city with stately buildings, broad avenues and historic public squares. Highlights include the majestic gate known as Porte de Bourgogne, the stained glass windows of Bordeaux Cathedral, the 12th-century Romanesque basilica and the impressive Hôtel de Ville, or City Hall. But no visit to Bordeaux is complete without an acknowledgment of what makes this region of France known worldwide – wine! Wine lovers everywhere will recognize appellations such as Pauillac, St. Emilion, Margaux and Sauternes.

Scotland’s capital is a city of handsome Georgian buildings, many architectural highlights and two UNESCO World Heritage sites. The first is Edinburgh Castle and the medieval Royal Mile, Scotland’s most visited site. Edinburgh’s Old Town and New Town are also part of this designation. Perched on an extinct volcano, Edinburgh Castle affords unrivaled views of the city, and its Esplanade is where the spectacle of the Royal Military Tattoo takes place every August as part of the Edinburgh Festival.

Situated where the Seine estuary meets the English Channel, Honfleur has been an important port of trade and defense for centuries. Tall, narrow buildings line cobblestone streets in the Vieux Bassin, the historic harbor, and attract Parisians on summer weekends. Look up for the 15th-century wooden spire of the Église Saint-Étienne, the oldest church in town and now a maritime museum. Contrast it with the Église Sainte-Catherine, built entirely of wood by the town’s shipbuilders. Honfleur has a long tradition of inspiring artists in the impressionist school.

The friendly village of Invergordon is your gateway to the Scottish Highlands. Visit Cawdor Castle, built in the 14th century and considered one of the most stately homes in the Highlands. The founding family, the Thanes of Cawdor, live there to this day. Next up is Dunrobin Castle, the ancestral home of the Clan Sutherland and one of the oldest inhabited houses in Scotland, featuring stunning formal gardens that run down to the sea.

Kirkwall is the largest settlement and capital of Orkney, an archipelago in the north of Scotland with history tracing back to Norse times in the 11th century. With history such as this, ancient archaeological sites are the highlight of a visit. The most important monuments can be found at the Heart of Neolithic Orkney, designated a UNESCO World Heritage site. The Ring of Brodgar is one of the finest known truly circular Neolithic stone rings. Other sites that are fascinating to tour are Maeshowe, the Standing Stones of Stenness and the ancient Neolithic village of Skara Brae.

Portugal’s capital on the Atlantic Ocean is comprised of several key districts built on seven hills. A good place to begin is the historic Alfama district, a maze of medieval streets and alleyways leading to a hilltop on which you will find the Castelo de São Jorge. One of Lisbon’s most popular attractions, the castle provides sweeping views over the city. Descend to the riverfront Baixa district to enjoy its shopping, restaurants and neoclassical architecture.

Las Palmas, the capital city of Gran Canaria island, is a bustling city that weaves the vibe of the Spanish mainland into a unique tapestry of life informed by world cultures including African, Chinese and Indian. A city of superlatives, it's one of Europe's biggest ports with one of the world's best climates and the cleanest air of any Spanish city according to a WHO study. Many also believe that the long, wide stretch of Las Canteras is one of the world's great urban beaches.

Guernsey is a self-governing British Crown Dependency, and one of the Channel Islands in the English Channel close to the French coast. The handsome town of Regency-style buildings is a short walk up from the pier and a delight to explore. Visit Castle Cornet, a fortress that has guarded the harbor for eight centuries. After visiting the five museums housed within, you’ll become an expert on Guernsey history. Another popular attraction is Hauteville House, the former home of the exiled 19th-century French literary giant and author of Les Miserables, Victor Hugo.